“Fifty percent less” can sound impressive. Without the starting number, the actual size of the difference remains unclear. This calculator shows both perspectives using your entries. It does not evaluate a study or predict what a medicine will do for you.

Your tool

This tool does not send your entries. They remain in this open page.

Compare proportions of people for the same event and follow-up period; do not enter repeat events or person-years.

Define the event first

The input counts people who experienced a clearly defined event at least once. In a real study, that might be a favourable or an unfavourable outcome. Both groups must refer to the same event over a comparable follow-up period. Repeated events per person and person-years do not fit this simple model of proportions.

Keep the group sizes

Enter the total number of people and the number with an event for both A and B. The groups may be different sizes. People with events cannot outnumber the group, and group size cannot be zero. The calculator therefore requires whole numbers and rejects incompatible values instead of returning an apparently meaningful answer.

Take a fictional example apart

Imagine 20 people with an event among 1,000 in A and ten among 1,000 in B. The proportions are two percent and one percent. B minus A is minus one percentage point. Relative to the two percent in A, that is fifty percent fewer. Both statements describe the same invented data from different perspectives.

Read signs and the reference correctly

The absolute difference is always displayed as B minus A. A minus sign means fewer events in B; whether that is beneficial depends on the event. Relative change is proportion B divided by proportion A, minus one, multiplied by one hundred. If A has no events, that ratio is undefined. The tool does not invent a percentage in its place.

Recognise what arithmetic cannot establish

A correctly calculated difference proves neither causation nor statistical certainty. The tool does not calculate confidence intervals or assess bias, missing data, dropouts or differences between participants. It cannot turn an association from an observational study into a treatment effect. Real study interpretation still requires methods, the comparator, follow-up and uncertainty alongside the figures.

Common questions

Can I compare average weight losses here?

No. The calculator uses proportions of people with an event, not average kilograms or mean weight changes.

Why is there no relative value when A has no events?

Division by zero is undefined. The absolute proportions and their difference can still be shown.

Sources & further reading

  1. IQWiG: Glossar – Risiko

Sources checked:

eu. infopoint editorial team

Researched and created with AI assistance. This article has not undergone individual review by a medical professional.

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